Báo cáo khoa học: Identification and characterization of novel PKA holoenzymes in human T lymphocytes
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Cyclic AMP-dependent protein kinase (PKA) is a holoenzyme that consistsof a regulatory (R) subunit dimer and two catalytic (C) subunits that arereleased upon stimulation by cAMP. Immunoblotting and immunoprecipita-tion of T-cell protein extracts, immunofluorescence of permeabilized T cellsand RT⁄PCR of T-cell RNA using C subunit-specific primers revealedexpression of two catalytically active PKA C subunits Ca1 (40 kDa) andCb2 (47 kDa) in these cells.
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Báo cáo khoa học: Identification and characterization of novel PKA holoenzymes in human T lymphocytes
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Báo cáo khoa học: Identification and characterization of novel PKA holoenzymes in human T lymphocytes
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