Báo cáo khoa học: Identification and structural characterization of a sialylated lacto-N-neotetraose structure in the lipopolysaccharide of Haemophilus influenzae
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A sialylated lacto-N-neotetraose (Sial-lNnT) structural unitwas identified and structurally characterized in the lipo-polysaccharide (LPS) from the genome-sequenced strainRoad (RM118) of the human pathogenHaemophilus influ-enzaegrown in the presence of sialic acid. A combination ofmolecular genetics, MS and NMR spectroscopy techniquesshowed that this structural unit extended from the proximalheptose residue of the inner core regionof theLPSmolecule.
Nội dung trích xuất từ tài liệu:
Báo cáo khoa học: Identification and structural characterization of a sialylated lacto-N-neotetraose structure in the lipopolysaccharide of Haemophilus influenzae
Nội dung trích xuất từ tài liệu:
Báo cáo khoa học: Identification and structural characterization of a sialylated lacto-N-neotetraose structure in the lipopolysaccharide of Haemophilus influenzae
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