Báo cáo khoa học: IMP1 interacts with poly(A)-binding protein (PABP) and the autoregulatory translational control element of PABP-mRNA through the KH III-IV domain
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Repression of poly(A)-binding protein (PABP) mRNA translation involvesthe formation of a heterotrimeric ribonucleoprotein complex by the bindingof PABP, insulin-like growth factor II mRNA binding protein-1 (IMP1)and theunrgene encoded polypeptide (UNR) to the adenine-rich autoregu-latory sequence (ARS) located at the 5¢ untranslated region of the PABP-mRNA.
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Báo cáo khoa học: IMP1 interacts with poly(A)-binding protein (PABP) and the autoregulatory translational control element of PABP-mRNA through the KH III-IV domain
Nội dung trích xuất từ tài liệu:
Báo cáo khoa học: IMP1 interacts with poly(A)-binding protein (PABP) and the autoregulatory translational control element of PABP-mRNA through the KH III-IV domain
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