Báo cáo khoa học: In vivo degradation of nitric oxide synthase (NOS) and heat shock protein 90 (HSP90) by calpain is modulated by the formation of a NOS–HSP90 heterocomplex
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We have shown previously that isolated heat shock protein 90 (HSP90)and nitric oxide synthase (NOS), once associated in a heterocomplex,become completely resistant to calpain digestion. In this study, it is shownthat, in vivo, under conditions of calpain activation, the protection of NOSdegradation occurs.
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Báo cáo khoa học: In vivo degradation of nitric oxide synthase (NOS) and heat shock protein 90 (HSP90) by calpain is modulated by the formation of a NOS–HSP90 heterocomplex
Nội dung trích xuất từ tài liệu:
Báo cáo khoa học: In vivo degradation of nitric oxide synthase (NOS) and heat shock protein 90 (HSP90) by calpain is modulated by the formation of a NOS–HSP90 heterocomplex
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