Báo cáo khoa học: Inhibition of the mitochondrial calcium uniporter by the oxo-bridged dinuclear ruthenium amine complex (Ru360) prevents from irreversible injury in postischemic rat heart
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Mitochondrial calcium overload has been implicated in the irreversibledamage of reperfused heart. Accordingly, we studied the effect of an oxy-gen-bridged dinuclear ruthenium amine complex (Ru360), which is a select-ive and potent mitochondrial calcium uniporter blocker, on mitochondrialdysfunction and on the matrix free-calcium concentration in mitochondriaisolated from reperfused rat hearts.
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Báo cáo khoa học: Inhibition of the mitochondrial calcium uniporter by the oxo-bridged dinuclear ruthenium amine complex (Ru360) prevents from irreversible injury in postischemic rat heart
Nội dung trích xuất từ tài liệu:
Báo cáo khoa học: Inhibition of the mitochondrial calcium uniporter by the oxo-bridged dinuclear ruthenium amine complex (Ru360) prevents from irreversible injury in postischemic rat heart
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scientific reports Report medicine traditional medicine Mitochondrial calcium overload has been implicated in the irreversible damage of reperfused heart. Accordingly we studied the effect of an oxy-gen-bridged dinuclear ruthenium amine complex (Ru360 ) which is a select-ive and potent mitochondrial calcium uniporter blocker on mitochondrial dysfunction and on the matrix free-calcium concentration in mitochondria isolated from reperfused rat hearts.Tài liệu liên quan:
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