Báo cáo khoa học: Insulin-induced proliferation of bladder cancer cells is mediated through activation of the epidermal growth factor system
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The mechanism behind the growth-promoting effect of insulin is a subjectof debate. Employing RT4 bladder cancer cells, we examined the cross-talkbetween insulin and the epidermal growth factor system. We found thatinsulin induced a time- and dose-dependent (25–1000 nmolÆL)1insulin)increase in mRNA expression of three ligands from the epidermal growthfactor system.
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Báo cáo khoa học: Insulin-induced proliferation of bladder cancer cells is mediated through activation of the epidermal growth factor system
Nội dung trích xuất từ tài liệu:
Báo cáo khoa học: Insulin-induced proliferation of bladder cancer cells is mediated through activation of the epidermal growth factor system
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