Báo cáo khoa học: Investigation of leucine-rich repeat kinase 2 Enzymological properties and novel assays
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Mutations in leucine-rich repeat kinase 2 (LRRK2) comprise the leadingcause of autosomal dominant Parkinson’s disease, with age of onset andsymptoms identical to those of idiopathic forms of the disorder. Several ofthese pathogenic mutations are thought to affect its kinase activity, sounderstanding the roles of LRRK2, and modulation of its kinase activity,may lead to novel therapeutic strategies for treating Parkinson’s disease.
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Báo cáo khoa học: Investigation of leucine-rich repeat kinase 2 Enzymological properties and novel assays
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Báo cáo khoa học: Investigation of leucine-rich repeat kinase 2 Enzymological properties and novel assays
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