Báo cáo khóa học: Isolation and characterization of the Xenopus HIVEP gene family
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The HIVEP gene family encodes for very large sequence-specific DNAbinding proteins containing multiple zincfingers. Three mammalian paralogous genes have beenidentified, HIVEP1,-2and -3, as well as the closely relatedDrosophilagene,Schnurri. These genes have been foundto directly participate in the transcriptional regulation of avariety of genes. Mammalian HIVEP members have beenimplicated in signaling by TNF-aand in the positive selec-tion of thymocytes, whileSchnurrihas been shown to be anessential component of theTGF-bsignalingpathway. ...
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Báo cáo khóa học: Isolation and characterization of the Xenopus HIVEP gene family
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Báo cáo khóa học: Isolation and characterization of the Xenopus HIVEP gene family
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