Báo cáo khoa học: Kinetic study of the HIV)1 DNA 3¢-end processing Single-turnover property of integrase
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The 3¢-processing of viral DNA extremities is the first step in the integra-tion process catalysed by human immunodeficiency virus (HIV)-1 integrase(IN). This reaction is relatively inefficient and processed DNAs are usuallydetectedin vitro under conditions of excess enzyme. Despite such experi-mental conditions, steady-state Michaelis–Menten formalism is oftenapplied to calculate characteristic equilibrium⁄kinetic constants of IN.
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Báo cáo khoa học: Kinetic study of the HIV)1 DNA 3¢-end processing Single-turnover property of integrase
Nội dung trích xuất từ tài liệu:
Báo cáo khoa học: Kinetic study of the HIV)1 DNA 3¢-end processing Single-turnover property of integrase
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