Báo cáo khoa học: Kinetics of the inhibition of neutrophil proteinases by recombinant elafin and pre-elafin (trappin-2) expressed in Pichia pastoris
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Elafin and its precursor, trappin-2 or pre-elafin, are specificendogenous inhibitors of human neutrophil elastase andproteinase 3 but not of cathepsin G. Both inhibitors belong,together with secretory leukocyte protease inhibitor, to thechelonianin family of canonical protease inhibitors of serineproteases. AcDNAcoding either elafin or its precursor,trappin-2, was fused in framewith yeasta-factor cDNAandexpressedinthePichiapastorisyeast expressionsystem.
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Báo cáo khoa học: Kinetics of the inhibition of neutrophil proteinases by recombinant elafin and pre-elafin (trappin-2) expressed in Pichia pastoris
Nội dung trích xuất từ tài liệu:
Báo cáo khoa học: Kinetics of the inhibition of neutrophil proteinases by recombinant elafin and pre-elafin (trappin-2) expressed in Pichia pastoris
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