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This work investigated the kinetics of catabolism and thecatabolic fate of the newly synthesized35S-labelled proteo-glycans present in explant cultures of tendon. Tissue fromthe proximal region of bovine deep flexor tendon was incu-bated with [35S]sulfate for 6 h and then placed in explantcultures for periods of up to 15 days. The amount of radi-olabel associatedwithproteoglycans and free [35S]sulfate lostto themediumand retained in thematrixwas determined foreach day in culture.
Nội dung trích xuất từ tài liệu:
Báo cáo khóa học: Large aggregating and small leucine-rich proteoglycans are degraded by different pathways and at different rates in tendon
