Báo cáo khoa học: Metabolic control of mitochondrial properties by adenine nucleotide translocator determines palmitoyl-CoA effects Implications for a mechanism linking obesity and type 2 diabetes
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Inhibition of the mitochondrial adenine nucleotide translocator (ANT) bylong-chain acyl-CoA esters has been proposed to contribute to cellular dys-function in obesity and type 2 diabetes by increasing formation of reactiveoxygen species and adenosine via effects on the coenzyme Q redox state,mitochondrial membrane potential (Dw) and cytosolic ATP concentrations.
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Báo cáo khoa học: Metabolic control of mitochondrial properties by adenine nucleotide translocator determines palmitoyl-CoA effects Implications for a mechanism linking obesity and type 2 diabetes
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Báo cáo khoa học: Metabolic control of mitochondrial properties by adenine nucleotide translocator determines palmitoyl-CoA effects Implications for a mechanism linking obesity and type 2 diabetes
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