Báo cáo khoa học: [Na+]i-induced c-Fos expression is not mediated by activation of the 5¢-promoter containing known transcriptional elements
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In vascular smooth muscle cells and several other cell types, inhibition ofNa+⁄K+-ATPase leads to the expression of early response genes, includingc-Fos. We designed this study to examine whether or not a putativeNa+i⁄K+i-sensitive element is located within the c-Fos5¢-UTR from )650to +103 containing all known response elements activated by ‘classic’stimuli, such as growth factors and Ca2+i-raising compounds.
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Báo cáo khoa học: [Na+]i-induced c-Fos expression is not mediated by activation of the 5¢-promoter containing known transcriptional elements
Nội dung trích xuất từ tài liệu:
Báo cáo khoa học: [Na+]i-induced c-Fos expression is not mediated by activation of the 5¢-promoter containing known transcriptional elements
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