Báo cáo khoa học: On the mechanism of action of the antifungal agent propionate Propionyl-CoA inhibits glucose metabolism in Aspergillus nidulans
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Propionate is used to protect bread and animal feed frommoulds. The mode of action of this short-chain fatty acidwas studied usingAspergillus nidulansas a model organism.The filamentous fungus is able to grow slowly on propio-nate, which is oxidized to acetyl-CoA via propionyl-CoA,methylcitrate and pyruvate. Propionate inhibits growth ofA. nidulanson glucose but not on acetate; the latter wasshown to inhibit propionate oxidation.
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Báo cáo khoa học: On the mechanism of action of the antifungal agent propionate Propionyl-CoA inhibits glucose metabolism in Aspergillus nidulans
Nội dung trích xuất từ tài liệu:
Báo cáo khoa học: On the mechanism of action of the antifungal agent propionate Propionyl-CoA inhibits glucose metabolism in Aspergillus nidulans
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