Báo cáo khoa học: Physiological relevance of the endogenous mono(ADP-ribosyl)ation of cellular proteins
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The mono(ADP-ribosyl)ation reaction is a post-translational modificationthat is catalysed by both bacterial toxins and eukaryotic enzymes, and thatresults in the transfer of ADP-ribose from bNAD+to various acceptorproteins. In mammals, both intracellular and extracellular reactions havebeen described; the latter are due to glycosylphosphatidylinositol-anchoredor secreted enzymes that are able to modify their targets, which includethe purinergic receptor P2X7, the defensins and the integrins. ...
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Báo cáo khoa học: Physiological relevance of the endogenous mono(ADP-ribosyl)ation of cellular proteins
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Báo cáo khoa học: Physiological relevance of the endogenous mono(ADP-ribosyl)ation of cellular proteins
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