Báo cáo khoa học: Plasminogen activator inhibitor type-1 inhibits insulin signaling by competing with avb3 integrin for vitronectin binding
Số trang: 8
Loại file: pdf
Dung lượng: 267.75 KB
Lượt xem: 2
Lượt tải: 0
Xem trước 2 trang đầu tiên của tài liệu này:
Thông tin tài liệu:
Functional cooperationbetween integrins andgrowth factorreceptors has been reported for several systems, oneofwhichis the modulation of insulin signaling by avb3 integrin.Plasminogen activator inhibitor type-1 (PAI-1), competeswithavb3 integrin for vitronectin (VN) binding. Here wereport that PAI-1, in a VN-dependent manner, prevents thecooperation of avb3 integrin with insulin signaling inNIH3T3 fibroblasts, resulting in a decrease in insulin-induced protein kinase B (PKB) phosphorylation, vascularendothelial growth factor (VEGF) expression and cellmigration. ...
Nội dung trích xuất từ tài liệu:
Báo cáo khoa học: Plasminogen activator inhibitor type-1 inhibits insulin signaling by competing with avb3 integrin for vitronectin binding
Nội dung trích xuất từ tài liệu:
Báo cáo khoa học: Plasminogen activator inhibitor type-1 inhibits insulin signaling by competing with avb3 integrin for vitronectin binding
Tìm kiếm theo từ khóa liên quan:
scientific reports Report medicine traditional medicine intermediate cells cell proliferation medical analysisGợi ý tài liệu liên quan:
-
9 trang 20 0 0
-
Encyclopedia of Medical Anthropology
1119 trang 19 0 0 -
Ebook Cancer biology (3/E): Part 2
165 trang 19 0 0 -
Báo cáo khoa học: Programmed cell death Apoptosis and alternative deathstyles
13 trang 19 0 0 -
63 trang 19 0 0
-
11 trang 16 0 0
-
12 trang 15 0 0
-
Rebuilding the Research Capacity at HUD
237 trang 14 0 0 -
Báo cáo khoa học: Lpx1p is a peroxisomal lipase required for normal peroxisome morphology
11 trang 14 0 0 -
6 trang 14 0 0