Báo cáo khoa học: Production and characterization of a noncytotoxic deletion variant of the Aspergillus fumigatus allergen Aspf1 displaying reduced IgE binding
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Aspergillus fumigatusis responsible for many allergic respiratory diseases,the most notable of which )due to its severity)is allergic bronchopulmo-nary aspergillosis. Aspf1 is a major allergen of this fungus: this 149-aminoacid protein belongs to the ribotoxin family, whose best characterizedmember isa-sarcin (EC 3.1.27.10). The proteins of this group are cytotoxicribonucleases that degrade a unique bond in ribosomal RNA impairingprotein biosynthesis.
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Báo cáo khoa học: Production and characterization of a noncytotoxic deletion variant of the Aspergillus fumigatus allergen Aspf1 displaying reduced IgE binding
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Báo cáo khoa học: Production and characterization of a noncytotoxic deletion variant of the Aspergillus fumigatus allergen Aspf1 displaying reduced IgE binding
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