Báo cáo khoa học: Prokaryotic and eukaryotic DNA helicases Essential molecular motor proteins for cellular machinery
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NA helicases are ubiquitous molecular motor proteinswhich harness the chemical free energy of ATPhydrolysis tocatalyze the unwinding of energetically stable duplex DNA,and thus play important roles in nearly all aspects of nucleicacid metabolism, including replication, repair, recombina-tion, and transcription. They break the hydrogen bondsbetween the duplex helix and move unidirectionally alongthe bound strand. All helicases are also translocases andDNA-dependentATPases.Most contain conserved helicasemotifs that act as an engine to power DNA unwinding. ...
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Báo cáo khoa học: Prokaryotic and eukaryotic DNA helicases Essential molecular motor proteins for cellular machinery
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Báo cáo khoa học: Prokaryotic and eukaryotic DNA helicases Essential molecular motor proteins for cellular machinery
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