Báo cáo khoa học: Purification and characterization of Helicobacter pylori arginase, RocF: unique features among the arginase superfamily
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The urea cycle enzyme arginase (EC 3.5.3.1) hydrolyzesL-arginine to L-ornithine and urea. Mammalian arginasesrequire manganese, have a highly alkaline pH optimumand are resistant to reducing agents. The gastric humanpathogen,Helicobacter pylori, also has a complete ureacycle and contains therocFgene encoding arginase (RocF),which is involved in the pathogenesis ofH. pyloriinfection.Its arginase is specifically involved in acid resistance andinhibits host nitric oxide production.
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Báo cáo khoa học: Purification and characterization of Helicobacter pylori arginase, RocF: unique features among the arginase superfamily
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Báo cáo khoa học: Purification and characterization of Helicobacter pylori arginase, RocF: unique features among the arginase superfamily
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