Báo cáo khoa học: RNA helicase A interacts with nuclear factor jB p65 and functions as a transcriptional coactivator
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RNA helicase A (RHA), a member of DNA and RNAhelicase family containing ATPase activity, is involved inmany steps of gene expression such as transcription andmRNA export. RHA has been reported to bind directly tothe transcriptional coactivator, CREB-binding protein, andthe tumor suppressor protein, BRCA1, and links them toRNAPolymerase II holoenzyme complex. Using yeast two-hybrid screening, we have identified RHA as an interactingmolecule of the p65 subunit of nuclear factorjB(NF-jB).
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Báo cáo khoa học: RNA helicase A interacts with nuclear factor jB p65 and functions as a transcriptional coactivator
Nội dung trích xuất từ tài liệu:
Báo cáo khoa học: RNA helicase A interacts with nuclear factor jB p65 and functions as a transcriptional coactivator
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Report medicine traditional medicine scientific reports Structural biochemistry oxidation bacteriaTài liệu liên quan:
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