Báo cáo khoa học: Second messenger function and the structure–activity relationship of cyclic adenosine diphosphoribose (cADPR)
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Cyclic ADP-ribose (cADPR) is a Ca2+mobilizing second messenger foundin various cell types, tissues and organisms. Receptor-mediated formationof cADPR may proceed via transmembrane shuttling of the substrateNAD and involvement of the ectoenzyme CD38, or via so far unidentifiedADP-ribosyl cyclases located within the cytosol or in internal membranes.cADPR activates intracellular Ca2+release via type 2 and 3 ryanodinereceptors.
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Báo cáo khoa học: Second messenger function and the structure–activity relationship of cyclic adenosine diphosphoribose (cADPR)
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Báo cáo khoa học: Second messenger function and the structure–activity relationship of cyclic adenosine diphosphoribose (cADPR)
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