Báo cáo khoa học: Secondary transporters of the 2HCT family contain two homologous domains with inverted membrane topology and trans re-entrant loops
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The 2-hydroxycarboxylate transporter (2HCT) family of secondary trans-porters belongs to a much larger structural class of secondary transporterstermed ST3 which contains about 2000 transporters in 32 families. Thetransporters of the 2HCT family are among the best studied in the class.Here we detect weak sequence similarity between the N- and C-terminalhalves of the proteins using a sensitive method which uses a database con-taining the N- and C-terminal halves of all the sequences in ST3 andinvolves blastsearches of each sequence in the database against the wholedatabase. ...
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Báo cáo khoa học: Secondary transporters of the 2HCT family contain two homologous domains with inverted membrane topology and trans re-entrant loops
Nội dung trích xuất từ tài liệu:
Báo cáo khoa học: Secondary transporters of the 2HCT family contain two homologous domains with inverted membrane topology and trans re-entrant loops
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