Báo cáo khoa học: Secretion of macrophage urokinase plasminogen activator is dependent on proteoglycans
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The importance of proteoglycans for secretionof proteolyticenzymes was studied in the murine macrophage cell lineJ774. Untreated or 4b-phorbol 12-myristate 13-acetate(PMA)-stimulated macrophages were treated withhexyl-b-D-thioxyloside to interfere with the attachment ofglycosaminoglycan chains to their respective protein cores.Activation of the J774 macrophages with PMA resulted inincreased secretion of trypsin-like serine proteinase activity.
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Báo cáo khoa học: Secretion of macrophage urokinase plasminogen activator is dependent on proteoglycans
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Báo cáo khoa học: Secretion of macrophage urokinase plasminogen activator is dependent on proteoglycans
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