Phân tích tư tưởng của nhân dân qua đoạn thơ: Những người vợ nhớ chồng… Những cuộc đời đã hóa sông núi ta trong Đất nước của Nguyễn Khoa Điềm
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The Hsp90 molecular chaperone catalyses the final activa-tion step of many of themost important regulatory proteinsof eukaryotic cells. The antibiotics geldanamycin and rad-icicol act as highly selective inhibitors of in vivo Hsp90function through their ability to bindwithin the ADP/ATPbinding pocket of the chaperone. Drugs based on thesecompounds are now being developed as anticancer agents,their administration having the potential to inactivate sim-ultaneously several of the targets critical for counteractingmultistep carcinogenesis. ...
Nội dung trích xuất từ tài liệu:
Báo cáo khoa học: Sensitivity to Hsp90-targeting drugs can arise with mutation to the Hsp90 chaperone, cochaperones and plasma membrane ATP binding cassette transporters of yeast
