Báo cáo khoa học: Solution and membrane-bound chaperone activity of the diphtheria toxin translocation domain towards the catalytic domain
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During cell intoxication by diphtheria toxin, endosome acidification trig-gers the translocation of the catalytic (C) domain into the cytoplasm. Thisevent is mediated by the translocation (T) domain of the toxin. Previouswork suggested that the T domain acts as a chaperone for the C domainduring membrane penetration of the toxin.
Nội dung trích xuất từ tài liệu:
Báo cáo khoa học: Solution and membrane-bound chaperone activity of the diphtheria toxin translocation domain towards the catalytic domain"
Nội dung trích xuất từ tài liệu:
Báo cáo khoa học: Solution and membrane-bound chaperone activity of the diphtheria toxin translocation domain towards the catalytic domain"
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