Báo cáo khoa học: Squamous cell carcinoma of the breast: a case report

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Báo cáo khoa học: " Squamous cell carcinoma of the breast: a case report"World Journal of Surgical Oncology BioMed Central Open AccessCase reportSquamous cell carcinoma of the breast: a case reportElvira R Flikweert*1,3, Mans Hofstee2 and Mike SL Liem1Address: 1Deventer Hospital, Department of Surgery, Postbus 5001, 7400 GC Deventer, the Netherlands, 2Deventer Hospital, Department ofPathology, Postbus 5001, 7400 GC Deventer, the Netherlands and 3University Medical Center Groningen, Department of Surgery, Postbus 30.001,9700 RB Groningen, the NetherlandsEmail: Elvira R Flikweert* - elviraflikweert@hotmail.com; Mans Hofstee - M.Hofstee@dz.nl; Mike SL Liem - M.S.L.Liem@dz.nl* Corresponding authorPublished: 21 December 2008 Received: 10 September 2008 Accepted: 21 December 2008World Journal of Surgical Oncology 2008, 6:135 doi:10.1186/1477-7819-6-135This article is available from: http://www.wjso.com/content/6/1/135© 2008 Flikweert et al; licensee BioMed Central Ltd.This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0),which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Abstract Background: Squamous cells are normally not found inside the breast, so a primary squamous cell carcinoma of the breast is an exceptional phenomenon. There is a possible explanation for these findings. Case presentation: A 72-year-old woman presented with a breast abnormality suspected for breast carcinoma. After the operation the pathological examination revealed a primary squamous cell carcinoma of the breast. Conclusion: The presentation of squamous cell carcinoma could be similar to that of an adenocarcinoma. However, a squamous cell carcinoma of the breast could also develop from a complicated breast cyst or abscess. Therefore, pathological examination of these apparent benign abnormalities is mandatory.Background Case presentationSquamous cell carcinoma is a well known malignancy of A 72 years old white woman presented at the specializedthe skin and other organs surrounded with squamous outpatient clinic for breast diseases in the Deventer Hos-cells such as the esophagus and the anus. Squamous cell pital in Deventer, The Netherlands. Two weeks earlier, shecarcinoma of the breast is very rare. It is important to dis- had discovered a local swelling in her right breast, locatedcriminate this entity from malignancies of the skin of the behind the nipple. There was no retracted nipple, norbreast or metastasis of a squamous cell carcinoma some- excretion from the nipple. The skin had been red for awhere else in the body. In the literature only some small while, but this had disappeared spontaneously. Theseries are reported [1-3]. Reported incidences of primary woman was postmenopausal, had given birth to 4 chil-squamous cell carcinoma of the breast vary between 0,1% dren to whom she had breastfed two. Her family history isto less than 0,04% of all breast carcinomas [1-3]. We relevant for breast cancer, her daughter had breast cancerreport a case of primary squamous cell carcinoma of the when she was thirty-five years old. The patient historybreast presenting as a usual breast carcinoma. However, in mentioned a cholecystectomy, hysterectomy and appen-the literature there are examples of less typical presenta- dectomy and hypertension and atrial fibrillation. She hadtions, for example starting as an abscess [3]. used some medication against hypertension, an anticoag- ulant and a tranquilizer. Page 1 of 4 ...