Báo cáo khoa học: Structure, expression and regulation of the cannabinoid receptor gene (CB1 ) in Huntington's disease transgenic mice
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Loss of cannabinoid receptors (CB1) occurs prior to neuro-degeneration in Huntington’s disease (HD). The levels anddistribution of CB1 RNA were equivalent in 3-week-oldmice regardless of genotype demonstrating that the specificfactors and appropriate chromatin structure that lead to thetranscription ofCB1were present in the striatum of youngR6/2 and R6/1 transgenic HD mice.
Nội dung trích xuất từ tài liệu:
Báo cáo khoa học: Structure, expression and regulation of the cannabinoid receptor gene (CB1 ) in Huntington’s disease transgenic mice
Nội dung trích xuất từ tài liệu:
Báo cáo khoa học: Structure, expression and regulation of the cannabinoid receptor gene (CB1 ) in Huntington’s disease transgenic mice
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