Phân tích tư tưởng của nhân dân qua đoạn thơ: Những người vợ nhớ chồng… Những cuộc đời đã hóa sông núi ta trong Đất nước của Nguyễn Khoa Điềm
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The structure–activity relations of a series of syntheticphenoxazone drugs with aminoalkyl side chains of variablelength and different terminal groups were investigated byexamining their biological activity and DNA complexationaffinity. Biological activitywas determined fromtheir abilityto induce apoptosis and cell cycle perturbations (activationof cell cycle checkpoints) using the human malignantMOLT-3 cell line. The thermodynamic parameters of drug–DNA complexation were determined by differential scan-ning calorimetry....
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Báo cáo khoa học: Structure–activity relation for synthetic phenoxazone drugs Evidence for a direct correlation between DNA binding and pro-apoptotic activity
