Báo cáo khoa học: The C-terminal region of the proprotein convertase 1⁄ 3 (PC1⁄ 3) exerts a bimodal regulation of the enzyme activity in vitro
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The proprotein convertase PC1⁄3 preferentially cleaves its substrates in thedense core secretory granules of endocrine and neuroendocrine cells. Sim-ilar to most proteinases synthesized first as zymogens, PC1⁄3 is synthesizedas a larger precursor that undergoes proteolytic processing of its signalpeptide and propeptide.
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Báo cáo khoa học: The C-terminal region of the proprotein convertase 1⁄ 3 (PC1⁄ 3) exerts a bimodal regulation of the enzyme activity in vitro
Nội dung trích xuất từ tài liệu:
Báo cáo khoa học: The C-terminal region of the proprotein convertase 1⁄ 3 (PC1⁄ 3) exerts a bimodal regulation of the enzyme activity in vitro
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