Phân tích tư tưởng của nhân dân qua đoạn thơ: Những người vợ nhớ chồng… Những cuộc đời đã hóa sông núi ta trong Đất nước của Nguyễn Khoa Điềm
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HR12 is anovel farnesyltransferase inhibitor (FTI).Wehaveshown previously that HR12 induces phenotypic reversionof H-rasV12-transformed Rat1 (Rat1/ras) fibroblasts. Thisreversion was characterized by formation of cell–cell con-tacts, focal adhesions and stress fibers. Here we show thatHR12 inhibits anchorage independent and dependentgrowth of Rat1/ras cells. HR12 also suppresses motility andproliferation of Rat1/ras cells, in a wound healing assay.Rat1 fibroblasts transformed with myristoylated H-rasV12(Rat1/myr-ras) were resistant to HR12....
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Báo cáo khoa học: The inhibition of Ras farnesylation leads to an increase in p27Kip1 and G1 cell cycle arrest
