Báo cáo khoa học: The role of electrostatic interactions in the antitumor activity of dimeric RNases
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The cytotoxic action of some ribonucleases homologous to bovine pancre-atic RNase A, the superfamily prototype, has interested and intriguedinvestigators. Their ribonucleolytic activity is essential for their cytotoxicaction, and their target RNA is in the cytosol. It has been proposed thatthe cytosolic RNase inhibitor (cRI) plays a major role in determining theability of an RNase to be cytotoxic.
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Báo cáo khoa học: The role of electrostatic interactions in the antitumor activity of dimeric RNases
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Báo cáo khoa học: The role of electrostatic interactions in the antitumor activity of dimeric RNases
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