Báo cáo khoa học: The role of evolutionarily conserved hydrophobic contacts in the quaternary structure stability of Escherichia coli serine hydroxymethyltransferase
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Pyridoxal 5¢-phosphate-dependent enzymes may be grouped into five struc-tural superfamilies of proteins, corresponding to as many fold types. Thefold type I is by far the largest and most investigated group. An importantfeature of this fold, which is characterized by the presence of two domains,appears to be the existence of three clusters of evolutionarily conservedhydrophobic contacts.
Nội dung trích xuất từ tài liệu:
Báo cáo khoa học: The role of evolutionarily conserved hydrophobic contacts in the quaternary structure stability of Escherichia coli serine hydroxymethyltransferase
Nội dung trích xuất từ tài liệu:
Báo cáo khoa học: The role of evolutionarily conserved hydrophobic contacts in the quaternary structure stability of Escherichia coli serine hydroxymethyltransferase
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