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Báo cáo khoa học: Three novel carp CXC chemokines are expressed early in ontogeny and at nonimmune sites

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Three novel CXC chemokines were identified in commoncarp (Cyprinus carpioL.) through homology cloning. Phy-logenetic analyses show that one of the three CXC chemo-kines is an unambiguous orthologue ofCXCL14,whereasboth others are orthologues ofCXCL12,and were namedCXCL12aandCXCL12b. Percentages of amino acid iden-tity between each of these carp chemokines and their humanand mouse orthologues are markedly higher than thosereported previously for other carp CXC chemokines, sug-gestive of involvement invital processes, whichhave allowedfor relatively few structural changes. ...
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Báo cáo khoa học: Three novel carp CXC chemokines are expressed early in ontogeny and at nonimmune sites

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