Báo cáo khoa học: Tumor suppressor p16INK4a ) modulator of glycomic profile and galectin-1 expression to increase susceptibility to carbohydrate-dependent induction of anoikis in pancreatic carcinoma cells
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Expression of the tumor suppressor p16INK4aafter stable transfection canrestore the susceptibility of epithelial tumor cells to anoikis. This propertyis linked to increases in the expression and cell-surface presence of thefibronectin receptor. Considering its glycan chains as pivotal signals, weassumed an effect of p16INK4aon glycosylation.
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Báo cáo khoa học: Tumor suppressor p16INK4a ) modulator of glycomic profile and galectin-1 expression to increase susceptibility to carbohydrate-dependent induction of anoikis in pancreatic carcinoma cells
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Báo cáo khoa học: Tumor suppressor p16INK4a ) modulator of glycomic profile and galectin-1 expression to increase susceptibility to carbohydrate-dependent induction of anoikis in pancreatic carcinoma cells
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