Báo cáo khoa học: Uptake and metabolism of [3H]anandamide by rabbit platelets Lack of transporter?
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Anandamide is an endogenous ligand for cannabinoidreceptor and its protein-mediated transport across cellularmembranes has been demonstrated in cells derived frombrain as well as in cells of the immune system. This lipidis inactivated via intracellular degradation by a fatty acidamidohydrolase (FAAH). In the present study, we reportthat rabbit platelets, in contrast to human platelets, do notpossess a carrier-mediated mechanism for the transport of[3H]anandamide into the cell, i.e. cellular uptake was nottemperature dependent and its accumulation was not satu-rable. ...
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Báo cáo khoa học: Uptake and metabolism of [3H]anandamide by rabbit platelets Lack of transporter?
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Báo cáo khoa học: Uptake and metabolism of [3H]anandamide by rabbit platelets Lack of transporter?
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