Báo cáo khoa học: Use of lithium and SB-415286 to explore the role of glycogen synthase kinase-3 in the regulation of glucose transport and glycogen synthase
Số trang: 10
Loại file: pdf
Dung lượng: 426.94 KB
Lượt xem: 5
Lượt tải: 0
Xem trước 2 trang đầu tiên của tài liệu này:
Thông tin tài liệu:
Glycogen synthase kinase 3 (GSK3) is inactivated by insulinand lithium and, like insulin, Li also activates glycogensynthase (GS)viainhibition of GSK3. Li also mimics insu-lin’s ability to stimulate glucose transport (GT), an obser-vation that has led to the suggestion that GSK3 maycoordinate hormonal increases in GT and glycogen synthe-sis. Here we have used Li and SB-415286, a selective GSK3inhibitor, to establish the importance of GSK3 in the hor-monal activation of GT in terms of its effect on GS in L6myotubes and3T3-L1adipocytes. ...
Nội dung trích xuất từ tài liệu:
Báo cáo khoa học: Use of lithium and SB-415286 to explore the role of glycogen synthase kinase-3 in the regulation of glucose transport and glycogen synthase
Nội dung trích xuất từ tài liệu:
Báo cáo khoa học: Use of lithium and SB-415286 to explore the role of glycogen synthase kinase-3 in the regulation of glucose transport and glycogen synthase
Tìm kiếm theo từ khóa liên quan:
scientific reports Report medicine traditional medicine breast cancer medicine chemical reactionTài liệu liên quan:
-
Báo cáo khóa học: The structure–function relationship in the clostripain family of peptidases
10 trang 39 0 0 -
12 trang 38 0 0
-
7 trang 33 0 0
-
8 trang 33 0 0
-
CYP4B1 polymorphisms and the risk of breast cancer in Chinese women: A case-control study
14 trang 32 0 0 -
21 trang 32 0 0
-
22 trang 32 0 0
-
Báo cáo khoa học: Parsing in the Ahsmmeeofa Comldete Lexicon
2 trang 31 0 0 -
EVI1 expression in early-stage breast cancer patients treated with neoadjuvant chemotherapy
10 trang 30 0 0 -
8 trang 29 0 0