Báo cáo khoa học: Vaccination with prion peptide-displaying papillomavirus-like particles induces autoantibodies to normal prion protein that interfere with pathologic prion protein production in infected cells
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Prion diseases are fatal neurodegenerative disorders caused by proteina-ceous infectious pathogens termed prions (PrPSc). To date, there is no pro-phylaxis or therapy available for these transmissible encephalopathies.Passive immunization with monclonal antibodies recognizing the normalhost-encoded prion protein (PrPC) has been reported to abolish PrPScinfec-tivity and to delay onset of disease.
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Báo cáo khoa học: Vaccination with prion peptide-displaying papillomavirus-like particles induces autoantibodies to normal prion protein that interfere with pathologic prion protein production in infected cells
Nội dung trích xuất từ tài liệu:
Báo cáo khoa học: Vaccination with prion peptide-displaying papillomavirus-like particles induces autoantibodies to normal prion protein that interfere with pathologic prion protein production in infected cells
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