Báo cáo Y học: Acceleration of granulocyte colony-stimulating factor-induced neutrophilic nuclear lobulation by overexpression of Lyn tyrosine kinase
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Stimulation with granulocyte colony-stimulating factor(G-CSF) induces myeloid precursor cells to dierentiateinto neutrophils, and tyrosine phosphorylation of certaincellular proteins is crucial to this process. However, thesignaling pathways for neutrophil dierentiation are stillobscure. As the Src-like tyrosine kinase, Lyn, has beenreported to play a role in G-CSF-induced proliferation inavian lymphoid cells, we examined its involvement inG-CSF-induced signal transduction in mammalian cells....
Nội dung trích xuất từ tài liệu:
Báo cáo Y học: Acceleration of granulocyte colony-stimulating factor-induced neutrophilic nuclear lobulation by overexpression of Lyn tyrosine kinase
Nội dung trích xuất từ tài liệu:
Báo cáo Y học: Acceleration of granulocyte colony-stimulating factor-induced neutrophilic nuclear lobulation by overexpression of Lyn tyrosine kinase
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