Báo cáo Y học: Concerted regulation of free arachidonic acid and hormone-induced steroid synthesis by acyl-CoA thioesterases and acyl-CoA synthetases in adrenal cells
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Although the role of arachidonic acid (AA) in the regulationof steroidogenesis is well documented, the mechanism forAArelease isnot clear.Therefore, theaimof this studywas tocharacterize the role of an acyl-CoA thioesterase (ARTISt)and an acyl-CoA synthetase as members of an alternativepathway in the regulation of the intracellular levels of AA insteroidogenesis. Purified recombinant ARTISt releases AAfrom arachidonoyl-CoA (AA-CoA) with a Kmof 2lM.
Nội dung trích xuất từ tài liệu:
Báo cáo Y học: Concerted regulation of free arachidonic acid and hormone-induced steroid synthesis by acyl-CoA thioesterases and acyl-CoA synthetases in adrenal cells
Nội dung trích xuất từ tài liệu:
Báo cáo Y học: Concerted regulation of free arachidonic acid and hormone-induced steroid synthesis by acyl-CoA thioesterases and acyl-CoA synthetases in adrenal cells
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Report medicine traditional medicine scientific reports Structural biochemistry oxidation bacteriaTài liệu liên quan:
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