Báo cáo Y học: Conformationally constrained human calcitonin (hCt) analogues reveal a critical role of sequence 17–21 for the oligomerization state and bioactivity of hCt
Số trang: 12
Loại file: pdf
Dung lượng: 486.60 KB
Lượt xem: 6
Lượt tải: 0
Xem trước 2 trang đầu tiên của tài liệu này:
Thông tin tài liệu:
Calcitonin (Ct) is a 32-residue peptide hormone that ismainly known for its hypocalcemic effect and the inhibitionof bone resorption. Our previous studies have led to potent,side-chain lactam-bridged human Ct (hCt) analogues[Kapurniotu, A. Kayed, R., Taylor, J.W. & Voelter W.(1999) Eur. J. Biochem.265, 606±618; Kapurniotu, A. &Taylor, J.W. (1995)J. Med. Chem.38, 836±847]. We havehypothesized that a possibly type Ibturn/bsheet confor-mation in the region 17±21 may play an important role inhCt bioactivity. ...
Nội dung trích xuất từ tài liệu:
Báo cáo Y học: Conformationally constrained human calcitonin (hCt) analogues reveal a critical role of sequence 17–21 for the oligomerization state and bioactivity of hCt
Nội dung trích xuất từ tài liệu:
Báo cáo Y học: Conformationally constrained human calcitonin (hCt) analogues reveal a critical role of sequence 17–21 for the oligomerization state and bioactivity of hCt
Tìm kiếm theo từ khóa liên quan:
Traditional medicine Report medicine scientific reports breast cancer biological activities gastric cancerGợi ý tài liệu liên quan:
-
35 trang 38 0 0
-
12 trang 38 0 0
-
Báo cáo khóa học: The structure–function relationship in the clostripain family of peptidases
10 trang 37 0 0 -
Investigating the prognostic and predictive value of the type II cystatin genes in gastric cancer
17 trang 37 0 0 -
22 trang 32 0 0
-
CYP4B1 polymorphisms and the risk of breast cancer in Chinese women: A case-control study
14 trang 32 0 0 -
Báo cáo khoa học: Parsing in the Ahsmmeeofa Comldete Lexicon
2 trang 31 0 0 -
21 trang 31 0 0
-
EVI1 expression in early-stage breast cancer patients treated with neoadjuvant chemotherapy
10 trang 30 0 0 -
8 trang 29 0 0