Báo cáo y học: Femoral vein thrombophlebitis and septic pulmonary embolism due to a mixed anaerobic infection including Solobacterium moorei: a case report

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Báo cáo y học: " Femoral vein thrombophlebitis and septic pulmonary embolism due to a mixed anaerobic infection including Solobacterium moorei: a case report"Journal of Medical Case Reports BioMed Central Open AccessCase reportFemoral vein thrombophlebitis and septic pulmonary embolismdue to a mixed anaerobic infection including Solobacterium moorei:a case reportClaire A Martin1, Rohan S Wijesurendra1, Colin DR Borland1 andJohannis A Karas*2Address: 1Department of Medicine, Hinchingbrooke Hospital, Hinchingbrooke Heath Care NHS Trust, Huntingdon, Cambridgeshire, PE29 6NT,UK and 2Department of Microbiology, Hinchingbrooke Hospital, Hinchingbrooke Heath Care NHS Trust, Huntingdon, Cambridgeshire, PE296NT, UKEmail: Claire A Martin - claire.martin@hinchingbrooke.nhs.uk; Rohan S Wijesurendra - rohan.wijesurendra@hinchingbrooke.nhs.uk;Colin DR Borland - colin.borland@hinchingbrooke.nhs.uk; Johannis A Karas* - andreas.karas@hinchingbrooke.nhs.uk* Corresponding authorPublished: 2 July 2007 Received: 15 March 2007 Accepted: 2 July 2007Journal of Medical Case Reports 2007, 1:40 doi:10.1186/1752-1947-1-40This article is available from: http://www.jmedicalcasereports.com/content/1/1/40© 2007 Martin et al; licensee BioMed Central Ltd.This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0),which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Abstract Background: Primary foci of necrobacillosis infection outside the head and neck are uncommon but have been reported in the urogenital or gastrointestinal tracts. Reports of infection with Solobacterium moorei are rare. Case presentation: A 37-year-old male intravenous drug user was admitted with pain in his right groin, fever, rigors and vomiting following a recent injection into the right femoral vein. Admission blood cultures grew Fusobacterium nucleatum, Solobacterium moorei and Bacteroides ureolyticus. The patient was successfully treated with intravenous penicillin and metronidazole. Conclusion: This case report describes an unusual case of femoral thrombophlebitis with septic pulmonary embolism associated with anaerobic organisms in a groin abscess. Solobacterium moorei, though rarely described, may also have clinically significant pathogenic potential. Bacteroides spp are a heterogeneous group of Gram-nega-BackgroundFusobacterium nucleatum is a strictly anaerobic Gram-nega- tive obligate anaerobes. They are common gut commen-tive bacillus. It is generally considered to be a commensal sals but also opportunistic pathogens, mostly causingof the human oropharynx but is also documented to cause intra-abdominal abscesses in cases where the mucosalsevere infections including necrobacillosis [1]. In order to wall of the intestine is disrupted. They are also part of thepromote an anaerobic environment suitable for their oral flora and can cause peri-oral infection. Bacteroidesgrowth, Fusobacterium species aggregate human platelets contribute to development of a synergistic infection byand promote intravascular coagulation. The thrombo- reducing phagocytosis by polymorphs and through inac- tivation of antibiotics by β-lactamase production.embolic phenomena that result account for much of themorbidity associated with necrobacillosis. Solobacterium spp are anaerobic Gram-positive bacteria known to exist in the oropharynx, and probably involved Page 1 of 3 (page number not for citation purposes)Journal of Medical Case Reports 2007, 1:40 http://w ...