Báo cáo Y học: Modelling of simple and complex calcium oscillations From single-cell responses to intercellular signalling
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This review provides a comparative overview of recentdevelopments in the modelling of cellular calcium oscilla-tions. A large variety of mathematical models have beendeveloped for this wide-spread phenomenon in intra- andintercellular signalling. From these, a general model isextracted that involves six types of concentration variables:inositol 1,4,5-trisphosphate (IP3), cytoplasmic, endoplasmicreticulum and mitochondrial calcium, the occupied bindingsites of calcium buffers, and the fraction of active IP3receptor calciumrelease channels....
Nội dung trích xuất từ tài liệu:
Báo cáo Y học: Modelling of simple and complex calcium oscillations From single-cell responses to intercellular signalling
Nội dung trích xuất từ tài liệu:
Báo cáo Y học: Modelling of simple and complex calcium oscillations From single-cell responses to intercellular signalling
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