Báo cáo Y học: Permeability transition-independent release of mitochondrial cytochrome c induced by valinomycin
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To examine whether valinomycin induces a mitochondrialpermeability transition (PT), we investigated its effects onmitochondrial functions under various conditions. Theacceleration of mitochondrial respiration and swelling,induced by valinomycin, were found to be insensitive toinhibitors of the ordinary PT, indicating that valinomycindoes not induce the ordinary PT. Results of experimentsusingmitochondria isolated fromtransgenicmice expressinghuman bcl-2 also supported this conclusion.
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Báo cáo Y học: Permeability transition-independent release of mitochondrial cytochrome c induced by valinomycin
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Báo cáo Y học: Permeability transition-independent release of mitochondrial cytochrome c induced by valinomycin
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