BMP and activin membrane-bound inhibitor regulate connective tissue growth factor controlling mesothelioma cell proliferation
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Malignant mesothelioma (MM) is an aggressive mesothelial cell cancer type linked mainly to asbestos inhalation. MM characterizes by rapid progression and resistance to standard therapeutic modalities such as surgery, chemotherapy, and radiotherapy. Our previous studies have suggested that tumor cell-derived connective tissue growth factor (CTGF) regulates the proliferation of MM cells as well as the tumor growth in mouse xenograft models.
Tìm kiếm theo từ khóa liên quan:
BMC Cancer Malignant mesothelioma Cell cycle Cell-derived connective tissue growth factor Rapid progressionGợi ý tài liệu liên quan:
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