Can we use gonadotropin plasma concentration as surrogate marker for BMIrelated incomplete estrogen suppression in breast cancer patients receiving anastrozole?
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BMI has been suggested to impact on estrogenic activity in patients receiving anastrozole resulting in a reduced treatment efficacy in obese women. Current evidence in this regard is controversially discussed. Since estradiol is inversely correlated with gonadotropins it can be assumed that an impact of BMI is also reflected by gonadotropin plasma concentrations.
Nội dung trích xuất từ tài liệu:
Can we use gonadotropin plasma concentration as surrogate marker for BMIrelated incomplete estrogen suppression in breast cancer patients receiving anastrozole?
Nội dung trích xuất từ tài liệu:
Can we use gonadotropin plasma concentration as surrogate marker for BMIrelated incomplete estrogen suppression in breast cancer patients receiving anastrozole?
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