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Diseases of the Oral MucosaInfectionMost oral mucosal diseases involve microorganisms (Table 32-1).Table 32-1 Vesicular, Bullous, or Ulcerative Lesions of the Oral MucosaConditionUsual LocationClinical FeaturesCourseViral DiseasesPrimary acuteLip and oralLabialHeals that spontaneously in 10– days. Unlessherpetic mucosa gingival,(buccal, vesiclesgingivostomatitis [herpeslingual rupture and crust, 14 and vesicles quicklysimplex mucosa)intraoral secondarily infected, that lesions lasting 3virus (HSV) type 1, rarely type 2]ulcerate; weeks are not due to HSVextremely painful; primary acute gingivitis, infection.fever, malaise, foul odor, and cervical lymphadenopathy; occurs primarily in infants, children,and young adultsRecurrent herpes labialisMucocutane ...
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Chapter 032. Oral Manifestations of Disease (Part 3) Chapter 032. Oral Manifestations of Disease (Part 3) Diseases of the Oral Mucosa Infection Most oral mucosal diseases involve microorganisms (Table 32-1). Table 32-1 Vesicular, Bullous, or Ulcerative Lesions of the OralMucosa Condition Usual Clinical Course Location Features Viral Diseases Primary Lip and oral Labial Healsacute herpetic mucosa (buccal, vesicles that spontaneously in 10–gingivostomatitis gingival, lingual rupture and crust, 14 days. Unless[herpes simplex mucosa) and intraoral secondarily infected,virus (HSV) type 1, vesicles that lesions lasting >3rarely type 2] quickly ulcerate; weeks are not due to extremely painful; primary HSV acute gingivitis, infection. fever, malaise, foul odor, and cervical lymphadenopathy; occurs primarily in infants, children, and young adults Recurrent Mucocutane Eruption of Lasts about 1herpes labialis ous junction of lip, groups of vesicles week, but condition perioral skin that may coalesce, may be prolonged if then rupture and secondarily infected. crust; painful to If severe, topical or pressure or spicy oral antiviral may foods reduce healing time. Recurrent Palate and Small Healsintraoral herpes gingiva vesicles on spontaneously insimplex keratinized about 1 week. If epithelium that severe, topical or oral rupture and antiviral may reduce coalesce; painful healing time. Chickenpox Gingiva and Skin lesions Lesions heal(varicella-zoster oral mucosa may be spontaneously withinvirus) accompanied by 2 weeks. small vesicles on oral mucosa that rupture to form shallow ulcers; may coalesce to form large bullous lesions that ulcerate; mucosa may have generalized erythema Herpes Cheek, Unilateral Gradualzoster (reactivation tongue, gingiva, or vesicular eruptions healing withoutof varicella-zoster palate and ulceration in scarring unlessvirus) linear pattern secondarily infected; following sensory postherpetic distribution of neuralgia is common. trigeminal nerve or Oral acyclovir, one of its branches famcyclovir, or valacyclovir reduce healing time and postherpetic neuralgia Infectious Oral mucosa Fatigue, Oral lesionsmononucleosis ...