Chapter 054. Skin Manifestations of Internal Disease (Part 18)

Papulonodular Skin Lesions (Table 54-15) In the papulonodular diseases, the lesions are elevated above the surface of the skin and may coalesce to form plaques. The location, consistency, and color of the lesions are the keys to their diagnosis; this section is organized on the basis of color.Table 54-15 Papulonodular Skin Lesions According to Color GroupsI. WhiteA. Calcinosis cutisII. Skin-coloredA. Rheumatoid nodulesB. Neurofibromas (von Recklinghausens disease)C. Angiofibromas (tuberous sclerosis, MEN syndrome, type 1)D. Neuromas (MEN syndrome, type 2b)E. Adnexal tumors1. Basal cell carcinomas (nevoid basal cell carcinoma syndrome)2. Tricholemmomas (Cowden disease)F. Osteomas (Gardner syndrome)G. Primary cutaneous disorders1. Epidermal inclusion...
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Chapter 054. Skin Manifestations of Internal Disease (Part 18) Chapter 054. Skin Manifestations of Internal Disease (Part 18) Papulonodular Skin Lesions (Table 54-15) In the papulonodular diseases, the lesions are elevated abovethe surface of the skin and may coalesce to form plaques. The location,consistency, and color of the lesions are the keys to their diagnosis; this section isorganized on the basis of color. Table 54-15 Papulonodular Skin Lesions According to Color Groups I. White A. Calcinosis cutisII. Skin-colored A. Rheumatoid nodules B. Neurofibromas (von Recklinghausens disease) C. Angiofibromas (tuberous sclerosis, MEN syndrome, type 1) D. Neuromas (MEN syndrome, type 2b) E. Adnexal tumors 1. Basal cell carcinomas (nevoid basal cell carcinoma syndrome) 2. Tricholemmomas (Cowden disease) F. Osteomas (Gardner syndrome) G. Primary cutaneous disorders 1. Epidermal inclusion cysts 2. LipomasIII. Pink/translucenta A. Amyloidosis B. Papular mucinosisIV. Yellow A. Xanthomas B. Tophi C. Necrobiosis lipoidica D. Pseudoxanthoma elasticum E. Sebaceous adenomas (Torre syndrome)V. RedaA. Papules 1. Angiokeratomas (Fabry disease) 2. Bacillary angiomatosis (primarily in AIDS)B. Papules/plaques 1. Cutaneous lupus 2. Lymphoma cutis 3. Leukemia cutisC. Nodules 1. Panniculitis 2. Cutaneous polyarteritis nodosa 3. Systemic vasculitis D. Primary cutaneous disorders 1. Arthropod bites 2. Cherry hemangiomas 3. Infections, e.g., erysipelas, sporotrichosis 4. Polymorphous light eruption 5. Lymphocytoma cutis (pseudolymphoma)VI. Red-browna A. Sarcoidosis B. Sweets syndrome C. Urticaria pigmentosa D. Erythema elevatum diutinum (chronic leukocytoclastic vasculitis) E. Lupus vulgarisVII. Bluea A. Venous malformations (blue rubber bleb syndrome) B. Primary cutaneous disorders 1. Venous lake 2. Blue nevusVIII. Violaceous A. Lupus pernio (sarcoidosis) B. Lymphoma cutis C. Cutaneous lupusIX. Purple A. Kaposis sarcoma B. Angiosarcoma C. Palpable purpura X. Brown-blackb XI. Any color A. Metastasesa May have darker hue in more darkly pigmented individuals.b See also Hyperpigmentation.Note: MEN, multiple endocrine neoplasia.