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Adenovirus can be isolated from HSCT recipients at rates varying from 5 to 18%. Although hemorrhagic cystitis, pneumonia, gastroenteritis, and fatal disseminated infection have been reported, adenovirus infection, which (like CMV infection) usually occurs in the first or second month after transplantation, is often asymptomatic. A role for cidofovir therapy has been suggested, but the efficacy of this agent is unproven.
Infections with parvovirus B19 (presenting as anemia or occasionally as pancytopenia) and enteroviruses (sometimes fatal) can occur. Parvovirus infection may possibly respond to IVIg (Chap. 177). Intranasal pleconaril, a capsid-binding agent, is being studied for the treatment of enterovirus...
Nội dung trích xuất từ tài liệu:
Chapter 126. Infections in Transplant Recipients (Part 7)
