Comprehensive analysis of the role of ICOS ( CD278 ) in pan-cancer prognosis and immunotherapy
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The immunological checkpoint known as Inducible T Cell Costimulatory Factor (ICOS, Cluster of Differentiation, CD278) is activated and expressed on T cells. Both somatic cells and antigen-presenting cells expressed its ligand, ICOSL (including tumor cells in the tumor microenvironment). It is important for immunosuppression. Uncertainty surrounds the function of ICOS in tumor immunity.
Nội dung trích xuất từ tài liệu:
Comprehensive analysis of the role of ICOS ( CD278 ) in pan-cancer prognosis and immunotherapy
Nội dung trích xuất từ tài liệu:
Comprehensive analysis of the role of ICOS ( CD278 ) in pan-cancer prognosis and immunotherapy
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