Development and validation of polygenic risk scores for prediction of breast cancer and breast cancer subtypes in Chinese women
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Studies investigating breast cancer polygenic risk score (PRS) in Chinese women are scarce. The objectives of this study were to develop and validate PRSs that could be used to stratify risk for overall and subtype-specific breast cancer in Chinese women, and to evaluate the performance of a newly proposed Artificial Neural Network (ANN) based approach for PRS construction.
Nội dung trích xuất từ tài liệu:
Development and validation of polygenic risk scores for prediction of breast cancer and breast cancer subtypes in Chinese women
Nội dung trích xuất từ tài liệu:
Development and validation of polygenic risk scores for prediction of breast cancer and breast cancer subtypes in Chinese women
Tìm kiếm theo từ khóa liên quan:
BMC Cancer Breast cancer Polygenic risk score Single nucleotide polymorphisms Artifcial neural network Estrogen receptor-negative breast cancerGợi ý tài liệu liên quan:
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